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The Jeffersonian cyclopedia;

a comprehensive collection of the views of Thomas Jefferson classified and arranged in alphabetical order under nine thousand titles relating to government, politics, law, education, political economy, finance, science, art, literature, religious freedom, morals, etc.;

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5308. MISSOURI QUESTION, Geographical line.—[further continued].
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5308. MISSOURI QUESTION, Geographical line.—[further continued].

This momentous question,
like a fire bell in the night, awakened
and filled me with terror. I considered it
at once as the knell of the Union. It is
hushed, indeed, for the moment. But this
is a reprieve only, not a final sentence. A
geographical line, coinciding with a marked
principle, moral and political, once conceived
and held up to the angry passions of men,
will never be obliterated; and every new irritation
will mark it deeper and deeper.—
To John Holmes. Washington ed. vii, 159. Ford ed., x, 157.
(M. April. 1820)